Status:

COMPLETED

A Study of Lanadelumab in Persons With Hereditary Angioedema (HAE) Type I or II in North America

Lead Sponsor:

Shire

Collaborating Sponsors:

Takeda Development Center Americas, Inc.

Conditions:

Hereditary Angioedema (HAE)

Eligibility:

All Genders

Brief Summary

The main aim of this study is to compare the HAE attack rate before and after lanadelumab treatment was started in persons with Hereditary Angioedeme Type I or II. Data from participants will be coll...

Eligibility Criteria

Inclusion

  • Voluntarily provide written, signed, and dated (personally or via a legally-authorized representative) informed consent/and assent as applicable to participate in the study. Expression of understanding and agreement by fully informed parent(s) or legal guardian is required to permit the investigator to enroll a child in this study. The choice of the terms parental consent or parental permission in different regions may reflect local legal/regulatory and ethical considerations.
  • Diagnosis of HAE Type I or Type II.
  • Ability to use a mobile device for data collection in the study.

Exclusion

  • Participation in any interventional clinical trial at the time of enrollment.
  • Unable to provide written, signed, and dated informed consent/assent.
  • Investigator believes that the participant is not a suitable candidate for the study.

Key Trial Info

Start Date :

March 30 2019

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

October 22 2022

Estimated Enrollment :

168 Patients enrolled

Trial Details

Trial ID

NCT03845400

Start Date

March 30 2019

End Date

October 22 2022

Last Update

March 30 2023

Active Locations (29)

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Page 1 of 8 (29 locations)

1

Clinical Research Center of Alabama

Birmingham, Alabama, United States, 35209

2

Medical Research of Arizona

Scottsdale, Arizona, United States, 85248

3

University of California San Diego

San Diego, California, United States, 92122

4

AIRE Medical of Los Angeles

Santa Monica, California, United States, 90404