Status:
UNKNOWN
Mod of Cognitive Flexibility by tDCS, Tyrosine Polymorphisms in the COMT Gene
Lead Sponsor:
Sheffield Hallam University
Conditions:
Modulation of Cognitive Flexibility by Transcranial Direct Current Stimulation, Tyrosine Administration and Polymorphisms in the COMT Gene
Eligibility:
All Genders
18-30 years
Phase:
NA
Brief Summary
The current study would examine whether increases in endogenous dopaminergic activity via tyrosine and the (presumed) excitation of these by anodal tDCS of the dlPFC could causally be related to cogni...
Eligibility Criteria
Inclusion
- • Either male or female
- Between 18 and 30 years
- You are in good health
- You agree to fast overnight prior to testing
Exclusion
- • Are suffering from cardiac, hepatic, renal, neurological disorders
- Damaged or diseased skin on your face and scalp, or a sensitive scalp
- A history of alcohol or drug addiction, or severe psychiatric illness
- Drug treatment which may lower seizure threshold (i.e. epilepsy)
- Pregnancy
- Sleep deprivation (less than 6 hours a day)
- A history of migraine or headaches
- A history of taking antidepressants
- A history of taking tyrosine supplements
Key Trial Info
Start Date :
February 18 2019
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 30 2019
Estimated Enrollment :
32 Patients enrolled
Trial Details
Trial ID
NCT03845920
Start Date
February 18 2019
End Date
September 30 2019
Last Update
April 4 2019
Active Locations (1)
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1
Psychology labs
Sheffield, South Yorkshire, United Kingdom, S10 2BQ