Status:

COMPLETED

Evaluation of a Double Balloon Interventional Platform (DiLumen) for Complex Colonic ESD

Lead Sponsor:

Mercy Medical Center

Conditions:

Colonic Polyp

Eligibility:

All Genders

18-85 years

Phase:

NA

Brief Summary

The purpose of this randomized study is to compare ESD procedural time and cost facilitated with a dual balloon accessory device versus ESD procedures performed without the accessory device. Study is ...

Detailed Description

This is a prospective, post-market, randomized clinical trial comparing colonic ESD procedures utilizing the DiLumen™ Endolumenal Interventional Platform to colonic ESD procedures that are performed w...

Eligibility Criteria

Inclusion

  • Men or women 18-85 years of age.
  • Have ability to understand the requirements of the study and provide written informed consent
  • Suspected complex adenomatous polyps in the large intestine defined as sessile or polypoid lesions 2 cm and larger in size.
  • No medical contraindication to endoscopic submucosal dissection (ESD).

Exclusion

  • Contraindication to colonoscopy, such as active colitis, diverticulitis, perforation, or stricture.
  • History of open or laparoscopic colorectal surgery.
  • History of Inflammatory Bowel Disease (IBD).
  • Any medical or surgical condition that would preclude the endoscopic removal of the polyp.
  • Anatomy or other factors that prohibit safe access to the large intestine such as previous radiation therapy to the affected area, known colonic strictures, extensive colonic diverticuli, etc.
  • History of AIDS, HIV, or active hepatitis.
  • History of mental illness, including psychological or neurological conditions (addiction to substances such as alcohol. e.g.) that in the investigator's opinion would pre-empt their ability or willingness to participate in the study.
  • Patients who are pregnant or lactating.
  • Currently involved in another investigational product for similar purposes.

Key Trial Info

Start Date :

February 19 2019

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 10 2020

Estimated Enrollment :

147 Patients enrolled

Trial Details

Trial ID

NCT03846609

Start Date

February 19 2019

End Date

December 10 2020

Last Update

December 11 2020

Active Locations (1)

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Mercy Medical Center

Baltimore, Maryland, United States, 21202