Status:
COMPLETED
Novel MRI Sequence MR Fingerprinting in Breast MRI Feasibility Study
Lead Sponsor:
UNC Lineberger Comprehensive Cancer Center
Conditions:
Breast Screening
Eligibility:
FEMALE
18-99 years
Phase:
NA
Brief Summary
The purpose of this study is to evaluate potential clinical efficacy of a novel magnetic resonance imaging (MRI) approach, MR fingerprinting, capable of providing quantitative measures of important ti...
Detailed Description
This is a feasibility study of the use of the additional MR fingerprinting (MRF) scanning sequence with a total of 12 minutes scanning time to our clinical screening breast DCE MRI examination before ...
Eligibility Criteria
Inclusion
- English-speaking patients
- Ages 18 to 99 years old
- Scheduled to undergo a screening breast MRI study
- Capable and willing to provide signed informed consent
Exclusion
- Claustrophobia
- Presence of pacemaker, intracranial aneurysm clip, bladder stimulator, cochlear implant or metal near eyes or near pelvis that would create excessive imaging artifact
- Known hypersensitivity to contrast agent or to any component of contrast agent refractory to standard medications (antihistamines, steroids)
- Impaired kidney function (serum creatinine level \> 1.8 mg/dl or a glomerular filtration rate \< 60 as approximated using serum creatinine levels) unless anuric and on dialysis.
- Inability to tolerate MRI (e.g., inability to lie flat for \>1 hour)
- Pregnancy or lactating female
- Previous history of mastectomy or lumpectomy
- Breast enhancements (i.e. implants)
Key Trial Info
Start Date :
February 18 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 21 2022
Estimated Enrollment :
28 Patients enrolled
Trial Details
Trial ID
NCT03846947
Start Date
February 18 2019
End Date
June 21 2022
Last Update
May 11 2023
Active Locations (1)
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1
University of North Carolina at Chapel Hill
Chapel Hill, North Carolina, United States, 27599