Status:
COMPLETED
Microcirculatory Vasomotor Changes in Type 2 Diabetes With Peripheral Neuropathy
Lead Sponsor:
University of Avignon
Conditions:
Diabetic Neuropathy Peripheral
Small Vessel Disease of Diabetes Mellitus
Eligibility:
All Genders
40-75 years
Phase:
NA
Brief Summary
Microcirculatory flow is subject to cyclic changes under the influence of heart rate, respiration, myogenic activity, neurogenic factors and endothelial factors. Microcirculatory oscillations (vasomot...
Detailed Description
All the subjects will benefit from a: * clinical: diabetes duration, treatments * anthropometric: weight, height, BMI * level of physical activity by means of the International Physical Activity Ques...
Eligibility Criteria
Inclusion
- For diabetic patients, HbA1C \>6.5 and diabetes duration \>5years
- For healthy control no diabetes mellitus, no cardiovascular or renal pathology
Exclusion
- nondiabetic neuropathy
- on medication known to affect microcirculation
- presence of active foot ulcer or wound healing history \<3months
- inability to walk 6 minutes
- alcohol consumption of more than 3 units per day
Key Trial Info
Start Date :
February 4 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 30 2020
Estimated Enrollment :
108 Patients enrolled
Trial Details
Trial ID
NCT03847779
Start Date
February 4 2019
End Date
June 30 2020
Last Update
November 13 2020
Active Locations (1)
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1
Centre Hospitalier Henri Duffaut
Avignon, France, 84 000