Status:
COMPLETED
Multi-chip Meta-analysis of Parkinson's Disease for Clinical Validation of Small Samples of Key Genes in Disease
Lead Sponsor:
Zhujiang Hospital
Conditions:
Parkinson's Disease
Eligibility:
All Genders
18+ years
Brief Summary
The research team used meta-analytical statistical methods to integrate the results of different research groups on Parkinson's disease, using meta-analysis to find key genes related to the pathogenes...
Detailed Description
Parkinson's disease (PD) is a relatively common degenerative disease of the central nervous system. As society gradually becomes aging, the number of PD patients is increasing, but its exact pathogene...
Eligibility Criteria
Inclusion
- PD group：
- Patients who meet the 2016 China Parkinson's diagnostic criteria and the 2015 International Parkinson's and Movement Disorders Association (MDS) Parkinson's disease diagnostic criteria
- Newly diagnosed primary PD patients, diagnosed within 3-6 months
- Informed consent to the study
- Age \> 18 older
- Non-PD group:
- Age, gender-matched PD group
- Non-PD, non-PDS, non-neurological degenerative disease, patients without inflammatory disease and related family history
- Informed consent to the study
- Age \> 18 older
Exclusion
- Severe craniocerebral trauma patients
- Disturbance of consciousness
- Severe organic diseases, cerebral hemorrhage, cerebral thrombosis, severe coronary heart disease and lung disease, severe liver and kidney dysfunction, severe diabetes, severe hearing And visual impairment
- History of severe brain tumors, encephalitis or brain surgery
Key Trial Info
Start Date :
February 25 2019
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
February 20 2021
Estimated Enrollment :
238 Patients enrolled
Trial Details
Trial ID
NCT03848455
Start Date
February 25 2019
End Date
February 20 2021
Last Update
July 28 2023
Active Locations (1)
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1
Zhujiang Hospiatal
Guangzhou, Guangdong, China, 510000