Status:
UNKNOWN
A Pathophysiological Study of the Postprandial Human Liver (PLS)
Lead Sponsor:
Copenhagen University Hospital, Hvidovre
Collaborating Sponsors:
University of Copenhagen
Conditions:
Cirrhosis
Fatty Liver
Eligibility:
All Genders
18-85 years
Brief Summary
Fatty liver disease is a globally widespread disease The identification of valid biomarkers and targets for potential treatments requires in-depth knowledge about the pathophysiology of the postprandi...
Eligibility Criteria
Inclusion
- Healthy participants (WP 1 , WP 4 , WP 5 )
- Inclusion criteria: Healthy adults, 20 - 40 years old, non-smoker, BMI 20-25 kg/m2 , no chronical illnesses, no medication.
- Exclusion criteria: Blood donation within the past 3 months, acute illness within 2 weeks
- NAFLD ( WP 2)
- Inclusion criteria: Patients with clinical diagnosis of NAFL and indication for liver biopsy Exclusion criteria: Malignant disease, acute illness within the past 2 weeks.
- Cirrhosis (WP 3)
- Inclusion criteria: Patients with clinical diagnosis of cirrhosis and indication for liver biopsy.
- Exclusion criteria:Malignant disease, acute illness within the past 2 weeks.
Exclusion
Key Trial Info
Start Date :
March 2 2019
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
January 1 2025
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT03849235
Start Date
March 2 2019
End Date
January 1 2025
Last Update
January 22 2021
Active Locations (1)
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1
Gastrounit, Copenhagen University Hospital Hvidovre
Hvidovre, Capital Region Denmark, Denmark, 2650