Status:

WITHDRAWN

Lung Clearance Index and Lung Allograft Dysfunction

Lead Sponsor:

University of Zurich

Conditions:

Lung Transplantation

Chronic Lung Allograft Dysfunction

Eligibility:

All Genders

18+ years

Brief Summary

The aim of this project is to evaluate the ability of the lung clearance index (LCI) to detect early chronic lung allograft failure (CLAD) in adult lung transplant recipients over a period of 3 years.

Detailed Description

This single center study consists of three parts: 1. Characterisation of the Zurich lung transplant cohort regarding CLAD status and pulmonary function impairment (cross-sectional, study part I) 2. E...

Eligibility Criteria

Inclusion

  • Male and female lung transplant recipients
  • Written informed consent by the participant after information about the research project

Exclusion

  • Any contraindication to perform pulmonary function tests (e.g., persistent pneumothorax)
  • Acute airway infection
  • Chronic infection due to Burkholderia spp and nontuberculosis mykobacteria NTM

Key Trial Info

Start Date :

March 1 2019

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

September 30 2023

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT03850002

Start Date

March 1 2019

End Date

September 30 2023

Last Update

July 25 2019

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