Status:
RECRUITING
High Frame Rate Ultrasound in Heart Disease Assessment
Lead Sponsor:
London North West Healthcare NHS Trust
Conditions:
Coronary Artery Disease
Eligibility:
All Genders
18+ years
Brief Summary
The study will compare standard ultrasound images to high frame rate ultrasound images in patients with heart disease or with a low risk of heart disease to see if a higher frame rate of ultrasound ad...
Detailed Description
Following informed consent, patients recruited for the study will have an IV cannula inserted and will undergo imaging using 2 ultrasound systems. Standard clinical system (Philips IE33) will be used ...
Eligibility Criteria
Inclusion
- Inclusion criteria Either
- Ability to give informed consent
- age ≥18years and
- confirmed inducible wall motion / perfusion abnormality on previous stress echocardiogram
- known coronary artery disease - defined by presence of flow-limiting coronary stenosis(\>70% diameter stenosis) on coronary angiography.
- OR
- • patient who has been assessed as at low risk of having coronary heart disease
- Exclusion Criteria:
- Inability to undertake pharmacological stress, ie previously known intolerance to dipyridamole;
- Moderate or Severe aortic or mitral regurgitation or severe mitral stenosis;
- Significant pulmonary disease like severe COPD or pulmonary fibrosis;
- Atrial fibrillation;
- Inability to provide informed consent;
- Pregnancy and lactation;
- Known allergy to Sonovue
- Patients with second and third degree heart block, unless they have a pacemaker fitted
- Systolic BP \< 90
- Known Myasthenia Gravis
- Bronchial asthma
Exclusion
Key Trial Info
Start Date :
February 1 2022
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
September 30 2025
Estimated Enrollment :
25 Patients enrolled
Trial Details
Trial ID
NCT03850015
Start Date
February 1 2022
End Date
September 30 2025
Last Update
May 23 2025
Active Locations (1)
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1
London North West University Healthcare NHS Trust
Harrow, Middx, United Kingdom, HA1 3UJ