Status:
UNKNOWN
Accelerated Treatment of Endocarditis
Lead Sponsor:
Rigshospitalet, Denmark
Collaborating Sponsors:
Herlev Hospital
Nordsjaellands Hospital
Conditions:
Infectious Endocarditis
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Existing guidelines recommend a duration of antibiotic treatment of endocarditis of 4-6 weeks with one or two types of intravenously administered antibiotics. The long hospitalization increases severa...
Eligibility Criteria
Inclusion
- Patients hospitalized and diagnosed with bacterial, left-sided endocarditis as determined by the department clinician responsible based on the revised Duke criteria.
- The patient may be included \<14 days after beginning of relevant antibiotic treatment.
- Left-sided endocarditis with one of the following microorganisms: Streptococci; Enterococcus faecalis; Staphylococcus aureus.
- Patients ≥ 18 years.
Exclusion
- Known / suspected immunocompetence (HIV, chemotherapy, prednisolone treatment (\> 20 mg / day)).
- Incapability to give informed consent for participation.
- Relapse Endocarditis (Endocarditis with the same bacteria within six months).
Key Trial Info
Start Date :
January 17 2019
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 10 2023
Estimated Enrollment :
750 Patients enrolled
Trial Details
Trial ID
NCT03851575
Start Date
January 17 2019
End Date
December 10 2023
Last Update
February 6 2020
Active Locations (7)
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1
Skejby Sygehus
Aarhus, Denmark, 8200
2
Rigshospitalet
Copenhagen, Denmark, 2100
3
Gentofte Hospital
Copenhagen, Denmark
4
Herlev Hoslpital
Copenhagen, Denmark