Status:
TERMINATED
EEG-based Neurofeedback for Auditory Verbal Hallucinations (HALFEED)
Lead Sponsor:
University of Dublin, Trinity College
Collaborating Sponsors:
Actualise
Conditions:
Schizophrenia
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
This study's primary objective is to perform a randomized controlled pilot study to assess the feasibility of using EEG-based neurofeedback to reduce the severity of treatment-resistant auditory verba...
Detailed Description
Auditory verbal hallucinations (AVH) are experienced by up to 80% of patients diagnosed with schizophrenia, where they can cause significant occupational and social impairment. Current treatments are ...
Eligibility Criteria
Inclusion
- Are ≥ 18 years old
- Have a clinical diagnosis of a schizophrenia-spectrum disorder
- Have been experiencing auditory verbal hallucinations for at least one year
- Score 2 or more on the frequency item of the auditory hallucinations subscale of the Psychotic Symptom Ratings Scale (PSYRATS-AH; Haddock et al., 1999) at time of initial assessment (representing voices occurring at least once a day)
- Are deemed refractory to antipsychotic treatment (defined as still hearing voices despite 4-6 weeks of treatment with two different antipsychotics)
- Have been on a stable dose of antipsychotic medication for the three months prior to study enrolment
- Are right-handed, as determined by the Edinburgh Handedness Inventory (Oldfield, 1971)
- Are able to provide written, informed consent.
Exclusion
- Having a diagnosed substance abuse disorder
- Prior head injury with loss of consciousness for more than five minutes
- At immediate risk of harm to self or others.
Key Trial Info
Start Date :
March 1 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 25 2022
Estimated Enrollment :
4 Patients enrolled
Trial Details
Trial ID
NCT03852706
Start Date
March 1 2019
End Date
March 25 2022
Last Update
April 5 2022
Active Locations (1)
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1
Tallaght University Hospital / St. James' Hospital
Dublin, Ireland