Status:

COMPLETED

Prehabilitation of Frail Surgical Cancer Patients Using Remote Ischemic Preconditioning

Lead Sponsor:

Medical College of Wisconsin

Collaborating Sponsors:

National Institute on Aging (NIA)

Conditions:

Colon Cancer

Fragility

Eligibility:

All Genders

55-85 years

Phase:

NA

Brief Summary

This project will examine the efficacy of a simple, cost-effective, non-invasive intervention, called remote ischemic preconditioning (RIPC), to reduce frailty in pre-surgical, frail, elderly patients...

Detailed Description

Remote ischemic preconditioning (RIPC) was first described three decades ago as an intervention to protect vital organs from ischemic injury. RIPC occurs when a tissue is made transiently ischemic (5 ...

Eligibility Criteria

Inclusion

  • Be between the ages of 55-85
  • Have a positive diagnosis of colon cancer or suspected colon cancer based on pathology report
  • Be scheduled for curative resection of non-metastatic colon cancer
  • Have a 6-Minute Walk Test distance ≤80% of predicted value based on age and sex.

Exclusion

  • Condition which prevents walking
  • Any condition in which compression of the arm or transient ischemia is contraindicated (e.g. wounds in the arm)
  • Neurodegenerative disorder
  • Unstable angina in previous month
  • Myocardial infarction during previous month.

Key Trial Info

Start Date :

February 22 2019

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 1 2023

Estimated Enrollment :

17 Patients enrolled

Trial Details

Trial ID

NCT03853473

Start Date

February 22 2019

End Date

March 1 2023

Last Update

September 19 2024

Active Locations (1)

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1

Medical College of Wisconsin

Milwaukee, Wisconsin, United States, 53226