Status:
RECRUITING
Development of Novel Physiological CMR Methods in Health and Disease
Lead Sponsor:
Sheffield Teaching Hospitals NHS Foundation Trust
Conditions:
Heart Failure
Pulmonary Hypertension
Eligibility:
All Genders
20-80 years
Phase:
NA
Brief Summary
Physiological cardiovascular stress test plays a crucial role in the assessment of patients with suspected heart disease. There are several methods of cardiac physiological stress tests and each of th...
Detailed Description
For this study, the investigators will perform comprehensive physiological CMR in healthy volunteers and patients with suspected or known heart disease (coronary artery disease and heart failure). A s...
Eligibility Criteria
Inclusion
- Healthy Volunteers age 20 to 80, recruited from Sheffield Teaching Hospitals staff members
- Patients age 20 to 80 with suspected or known heart disease (group 1 to 5)
- Capable of giving written informed consent
Exclusion
- Inability to perform the study protocol secondary to severe heart failure requiring IV therapy
- Patients recruited in the suspected CAD and acute myocardial infarction arms of the study and in need for detection of ischaemia should not have any past medical history of MI, ACS or cardiomyopathy
- Patients with significant valvular heart disease will be excluded from any patient group
- Patient with in atrial fibrillation will be excluded
- Contraindication to MRI (as per standard MRI screening questionnaire issued to patients prior to clinical MRI procedures)
Key Trial Info
Start Date :
July 30 2018
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
January 1 2031
Estimated Enrollment :
135 Patients enrolled
Trial Details
Trial ID
NCT03854071
Start Date
July 30 2018
End Date
January 1 2031
Last Update
December 13 2024
Active Locations (1)
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1
Sheffield Teaching Hospitals NHS FT
Sheffield, England, United Kingdom, S10 2JF