Status:
COMPLETED
Micro-RNA Profile in Patients With Different Stages of Atherosclerosis According to CTA
Lead Sponsor:
I.M. Sechenov First Moscow State Medical University
Conditions:
Ischemic Heart Disease
Atherosclerosis
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
The main purpose of this single-center study is to determine the spectrum and levels of cardiospecific circulating microRNAs in patients with different stages of atherosclerosis according to 640-slice...
Detailed Description
The study will be conducted in two phases. Phase one. After signing the informed consent, patients with coronary heart disease, angina pectoris II-IV functional class, who underwent MSCT angiography o...
Eligibility Criteria
Inclusion
- Written informed consent of the patient to participate in the study;
- Age 18-80;
- The presence of medical indications for MSCT angiography of coronary arteries in connection with suspected coronary heart disease.
Exclusion
- Age less than 18 or more than 80;
- Pregnancy, breast-feeding;
- Patients who have not undergone (and do not plan) MSCT coronary angiography;
- Any surgical intervention on the heart in history;
- Severe heart failure (III-IV NYHA classes);
- History of myocardial infarction;
- The body mass index of 35 or more;
- More than twice the ALT and/or AST level;
- The presence of severe somatic pathology (except coronary atherosclerosis);
- Patient's refusal to participate in the study;
Key Trial Info
Start Date :
January 1 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 1 2020
Estimated Enrollment :
81 Patients enrolled
Trial Details
Trial ID
NCT03855891
Start Date
January 1 2019
End Date
October 1 2020
Last Update
December 22 2020
Active Locations (1)
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1
IMSechenovMMA
Moscow, Russia, 119991