Status:
UNKNOWN
Aerobic Exercise and Telomere Length in Patients With Heart Failure.
Lead Sponsor:
Hospital de Clinicas de Porto Alegre
Conditions:
Heart Failure
Eligibility:
All Genders
50-80 years
Phase:
NA
Brief Summary
The present study will analyze and compare the chronic effects of aerobic exercise in subjects with systolic heart failure on telomere length.
Detailed Description
Aging can be characterized by an organic and functional decrease, which is not related to disease, that is, a process that happens naturally over time. One of the markers of the aging process is telom...
Eligibility Criteria
Inclusion
- Primary diagnosis of HF with ejection fraction \<40%;
- Clinically stable patients with at least three months on optimal HF treatment;
- Age between 50 and 80 years;
- New York Heart Association (NYHA) functional class II to III;
- No contraindications to participate in an exercise program;
- Mentally able to understand instructions during the study.
Exclusion
- Severe valve disease;
- Peripheral artery disease with symptoms of intermittent claudication;
- Uncontrolled hypertension;
- Drug or alcohol abuse;
- Cognitive and/or osteomyoarticular conditions that prevent exercise;
- Logistical impossibility of attending the hospital intervention;
- Engaging in supervised physical exercise in the past three months;
- Do not complete the run-in period.
Key Trial Info
Start Date :
March 1 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 30 2021
Estimated Enrollment :
24 Patients enrolled
Trial Details
Trial ID
NCT03856736
Start Date
March 1 2021
End Date
December 30 2021
Last Update
January 11 2021
Active Locations (1)
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1
Hospital de Clínicas de Porto Alegre
Porto Alegre, Rio Grande do Sul, Brazil, 90035903