Status:

UNKNOWN

Effects of Green Light Exposure on Epileptic Spikes in Patients With Refractory Epilepsy

Lead Sponsor:

Boston Children's Hospital

Conditions:

Epilepsy

Epilepsy Intractable

Eligibility:

All Genders

6-30 years

Phase:

NA

Brief Summary

The purpose of this study is to obtain preliminary data in advance of a larger clinical trial aimed to test whether a single session of green light exposure can lead to a clinically significant reduct...

Detailed Description

The trial is designed to detect (1) change in spike frequency on EEG before and after exposure to low intensity green light, and (2) presence or absence of neurologic/systemic symptoms referable to ex...

Eligibility Criteria

Inclusion

  • 6 months-30 years of age
  • Epileptic spike frequency ≥1 epileptic spike per minute at baseline, as determined by scalp EEG recording
  • Admitted to the Boston Children's Hospital Epilepsy Long Term Monitoring Unit at the time of enrollment

Exclusion

  • Cataracts
  • Retinol disease
  • Any history of or currently not well controlled ophthalmic disease that prevents transmission from the retina to the optic nerve
  • Clinical seizure 4 hours or less before anticipated green light exposure

Key Trial Info

Start Date :

July 22 2019

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

June 1 2023

Estimated Enrollment :

16 Patients enrolled

Trial Details

Trial ID

NCT03857074

Start Date

July 22 2019

End Date

June 1 2023

Last Update

March 9 2022

Active Locations (1)

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1

Boston Children's Hospital

Boston, Massachusetts, United States, 02130