Status:

COMPLETED

Treatment of Gait Disorders in Children With Dravet Syndrome

Lead Sponsor:

Universiteit Antwerpen

Collaborating Sponsors:

University Hospital, Antwerp

KU Leuven

Conditions:

Dravet Syndrome

Severe Myoclonic Epilepsy of Infancy

Eligibility:

All Genders

3-25 years

Brief Summary

Dravet syndrome is a severe infantile onset epilepsy syndrome with a prevalence of 1/15.000 to 1/30.000. An infant with an apparently normal development presents around 6 months of age with a convulsi...

Detailed Description

The problem under investigation is the reduced functional mobility of patients with Dravet syndrome resulting from a crouch gait pattern. The solution, proposed in this research project, is the develo...

Eligibility Criteria

Inclusion

  • diagnosed with Dravet syndrome according to the criteria of Ceulemans and Cras (2004)
  • aged minimum 3 years and maximum 25 years at inclusion
  • having minimum 1 year of walking experience

Exclusion

  • severe epileptic seizure (status epilepticus or tonic-clonic insult over 3 min) within the 24 hours before the assessment
  • insufficient cooperation to perform 3D gait analysis
  • comorbidities of other neurological and/or orthopedic disorders not linked to Dravet syndrome

Key Trial Info

Start Date :

January 1 2017

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

December 31 2020

Estimated Enrollment :

50 Patients enrolled

Trial Details

Trial ID

NCT03857451

Start Date

January 1 2017

End Date

December 31 2020

Last Update

April 14 2022

Active Locations (3)

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Page 1 of 1 (3 locations)

1

University Hospital Antwerp

Antwerp, Belgium, 2160

2

University of Antwerp

Antwerp, Belgium, 2160

3

KU Leuven

Leuven, Belgium, 3000