Status:

ACTIVE_NOT_RECRUITING

Use of a Pre-Surgical Toolkit in Improving Surgical Care and Outcomes in Older Participants With Cancer

Lead Sponsor:

Alliance for Clinical Trials in Oncology

Collaborating Sponsors:

National Cancer Institute (NCI)

Conditions:

Malignant Neoplasm

Surgical Procedure, Unspecified

Eligibility:

All Genders

70+ years

Phase:

NA

Brief Summary

This trial studies how well the use of a pre-surgical toolkit (OPTI-Surg) works in improving surgical care and outcomes in older participants with cancer. In many elderly patients, surgery can greatly...

Detailed Description

PRIMARY OBJECTIVES: I. To compare 8-week postoperative function among elderly patients between sites randomized to implement the OPTI-Surg toolkit with or without a coach versus sites randomized to u...

Eligibility Criteria

Inclusion

  • Patients must have known or suspected cancer diagnosis and have one of the following cancer-directed operations planned:
  • Gastrectomy
  • Colectomy
  • Proctectomy
  • Esophagectomy
  • Pancreatectomy
  • Hepatectomy
  • Total cystectomy
  • Partial or total nephrectomy
  • Lung lobectomy/pneumonectomy
  • Patients with known metastatic disease with a plan for curative intent resection are eligible (e.g. curative liver resection for metastatic colorectal cancer).
  • Patients with double primaries undergoing planned curative operation for both are eligible (e.g. synchronous colon cancers undergoing colectomy to treat both).
  • Patients must be able to speak and complete questionnaires in English.

Exclusion

  • Patients undergoing emergent surgery are not eligible.
  • Patients under active treatment such as chemotherapy, targeted therapy, immunotherapy, radiation treatment, etc. for second primary, are not eligible.
  • Patients with second primary are not eligible.
  • Patients with known metastatic disease who are undergoing palliative resection are not eligible.
  • Patients with psychiatric illness or other mental impairment that would preclude their ability to give informed consent or to participate in the prehabilitation program are not eligible.

Key Trial Info

Start Date :

July 24 2019

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 1 2025

Estimated Enrollment :

325 Patients enrolled

Trial Details

Trial ID

NCT03857620

Start Date

July 24 2019

End Date

October 1 2025

Last Update

February 21 2025

Active Locations (44)

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Page 1 of 11 (44 locations)

1

Helen F Graham Cancer Center

Newark, Delaware, United States, 19713

2

MedStar Washington Hospital Center

Washington D.C., District of Columbia, United States, 20010

3

Augusta University Medical Center

Augusta, Georgia, United States, 30912

4

Memorial Health University Medical Center

Savannah, Georgia, United States, 31404

Use of a Pre-Surgical Toolkit in Improving Surgical Care and Outcomes in Older Participants With Cancer | DecenTrialz