Status:

UNKNOWN

LEC Proliferation in Vivo and In-vitro

Lead Sponsor:

Prim. Prof. Dr. Oliver Findl, MBA

Conditions:

Posterior Capsule Opacification

Eligibility:

All Genders

21-105 years

Brief Summary

Investigate the proliferative capacity of individual lens epithelium capsule specimens in vitro and correlate it to the risk of developing PCO

Detailed Description

Cataract, the clouding of the eye's lens, is still the leading cause of blindness worldwide. Until now surgery is the only therapy available for the disease. Cataract surgery is nowadays considered a ...

Eligibility Criteria

Inclusion

  • Age-related cataract.
  • Patients in the age group of 21 years and older.
  • Patients with uncomplicated cataract.
  • Patients without any relevant systemic or ocular morbidity.
  • Patients with well dilating pupils.
  • Written informed consent prior to any study specific action.

Exclusion

  • Patients with complicated cataract.
  • Patients with big differences in LOCS scale between the two eyes.
  • Patients having corneal pathology.
  • Patients with any form of ocular inflammation.
  • Patients with glaucoma, retinal pathologies.
  • Patients with traumatic cataracts, subluxated and dislocated lens, prior h/o ocular surgery, pseudoexfoliation.
  • Any intraoperative complications like posterior capsule rupture.
  • In case of pregnancy (pregnancy test will be taken preoperatively in women of reproductive age).

Key Trial Info

Start Date :

January 1 2019

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

January 1 2021

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT03857685

Start Date

January 1 2019

End Date

January 1 2021

Last Update

March 16 2020

Active Locations (1)

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Vienna Institute for Research in Ocular Surgery (VIROS)

Vienna, Austria, 1140

LEC Proliferation in Vivo and In-vitro | DecenTrialz