Status:
COMPLETED
Comparison of Postoperative Nociception Between NOL-guided and Standard Intraoperative Analgesia Based on Fentanyl
Lead Sponsor:
Victor Contreras, MSN
Conditions:
Pain, Postoperative
Opioid Use
Eligibility:
All Genders
18-50 years
Phase:
NA
Brief Summary
Pain is defined as an unpleasant sensory and emotional conscious experience, associated with actual or potential tissue damage. Nociception is the sympathetic response to noxious stimuli during uncons...
Detailed Description
Methodology: In this RCT double-blinded study will invite to 100 patients aged between 18 and 50 years admitted for elective surgery that is planned to require general anesthesia, with fentanyl as the...
Eligibility Criteria
Inclusion
- ASA I-II
- Elective abdominal surgery without a neuraxial block.
- Over 2 horas.
- Body Mass Index 18 - 30 kg/m2
Exclusion
- Cardiac surgery
- Cardiopathy
- Arrhythmia or use of pacemakers.
- Chronic Kidney disease (Plasma Crea \>1 mg/dL).
- Allergic to drugs of this study.
- Opioids or Non-inflammatory drugs over 5 days for two weeks before surgery.
- Neuropathies and dysautonomias.
- Beta-blockers and other drugs that act at the level of the sympathetic system the month prior to surgery.
- Chemotherapy.
Key Trial Info
Start Date :
March 15 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 23 2022
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT03858621
Start Date
March 15 2019
End Date
February 23 2022
Last Update
March 8 2022
Active Locations (1)
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1
Victor Contreras
Santiago, Santiago Metropolitan, Chile, 8420525