Status:

COMPLETED

Pressure Support and Positive End Expiratory Pressure During Spontaneous Breathing Trial

Lead Sponsor:

Hospices Civils de Lyon

Conditions:

Critically Ill Adult Patients With Difficult Weaning

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The aim of this study is to assess if a bundle associating pressure support and positive end-expiratory pressure during spontaneous breathing trial and detection by T-piece of patients with high-risk ...

Eligibility Criteria

Inclusion

  • Patient 18 years old or more
  • Intubated and ventilated in intensive care unit for more than 24 hours
  • Patient ready for weaning evaluation
  • Failure of a first T-piece SBT

Exclusion

  • Chronic neuromuscular disease
  • Guillain-Barré Syndrome
  • Central nervous system disease with consciousness disorder
  • Tracheostomy
  • Chronic disease with life expectancy less than 1 year
  • Pregnancy, breast feeding
  • Withholding life support regarding a reintubation
  • Prisoner or patient interned in psychiatric hospital
  • Guardianship
  • Language barrier
  • Lack of medical insurance
  • Lack of the patient's consent (or of the next of kin where appropriate)
  • Patient under an exclusion period after enrollment in another research study

Key Trial Info

Start Date :

May 10 2019

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 1 2023

Estimated Enrollment :

98 Patients enrolled

Trial Details

Trial ID

NCT03861117

Start Date

May 10 2019

End Date

June 1 2023

Last Update

December 19 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Hôpital de la Croix-Rousse

Lyon, France, 69317