Status:
COMPLETED
Hemodynamics During Induction of General Anesthesia With Medium or Low Remifentanil Doses.
Lead Sponsor:
Helse Fonna
Conditions:
Hemodynamic Instability
Anesthesia, General
Eligibility:
FEMALE
18-50 years
Phase:
PHASE4
Brief Summary
In this trial the investigators want to examine if there is any difference in hemodynamic stability during induction when comparing two low and a medium remifentanil dose and keeping propofol inductio...
Detailed Description
Typically, one or more adjuvant medications is administered during induction of general anesthesia. When anesthetic drugs are combined, the hypnotic effects are often synergistic. Propofol is associat...
Eligibility Criteria
Inclusion
- Gynecological procedure
- Age 18-50 years
- General anesthesia planned
- Systolic blood pressure \< 150 mmHg, HR \< 100 beats/min
Exclusion
- Pre-existing hypertension
- Diabetes
- Ischemic heart disease or cerebrovascular disease
- Heart valve disease
- Verified cardiac arrhythmia other than extrasystoles
- Verified anaemia with hemoglobin level below 9.0 gr/dl.
- Kidney or hepatic disease
- Hypersensitivity for propofol, soya, eggs or peanuts
- Pregnancy
- Poor health state
- Illicit substance use
- BMI \<20 or \>35 kg/m2
Key Trial Info
Start Date :
June 9 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 2 2022
Estimated Enrollment :
99 Patients enrolled
Trial Details
Trial ID
NCT03861377
Start Date
June 9 2020
End Date
February 2 2022
Last Update
March 21 2022
Active Locations (1)
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1
Kirurgisk Klinikk Anestesi
Haugesund, Rogaland, Norway, 5504