Status:
COMPLETED
Efficacy of Non-instrumental Pleural Chest Physiotherapy
Lead Sponsor:
Hôpital NOVO
Conditions:
Infectious Pleural Effusion
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The main purpose of this study is to assess efficacy of non instrumental pleural chest physiotherapy on the recovery of respiratory function, at hospital discharge or 15 days after beginning the pleur...
Detailed Description
Pleural effusions are defined by an abnormal amount of fluid in the pleural space. Those complicating a pneumonia are commonly encountered in pneumology departments, and their number are increasing. I...
Eligibility Criteria
Inclusion
- ≥ eighteen years old
- to be hospitalized for an infectious pleural outpouring
- to have a liquid pleural outpouring diagnosed by echography or to scan thoracic
- presence of a Exudate according to the criteria of Light, to have at least criteria:
- The ratio of pleural fluid protein to serum protein is greater than 0.5
- The ratio of pleural fluid Lactate dehydrogenase (LDH) and serum LDH is greater than 0.6
- The rate of pleural fluid LDH is \> 2/3 upper limit of normal serum LDH of the laboratory concerned
- presence of at least two of the following criteria:
- fever higher or equal 38°C (100.4°F)
- thoracic pain
- purulent sputum
- purulent pleural effusion at the time of the exploring pleural puncture
- hearth of crackling to the sounding
- Inflammatory syndrome (CRP\>15 mg/l and/or White blood cell \>10 000 /mm3)
- no known radiological hearth before
- Having undergone an evacuation gesture going back to less forty-eight hours: evacuation pleural puncture or repeated pleural punctures or pleural drainage allowing the evacuation of at least 100cc of pleural fluid
- Informed and having given its free, lit and express assent
- Patients with affiliation to the social security system
Exclusion
- Patient having undergone a thoracotomy or thoracoscopy in the six previous months
- Patient having a pneumothorax
- Patient reached of a tuberculosis
- Patient unable to carry out a measurement of the vital capacity by portable spirometer at the inclusion
- Pregnant woman or nursing
- Patient having a life expectancy lower than three months
- Proven or suspected pleural neoplasia disease
- Patient hemodynamically unstable
- Patient having a respiratory insufficiency requiring the introduction of an artificial ventilation
- Patient carrying a chronic respiratory insufficiency under non-invasive ventilation with the long course
- Patient unable to carry out the exercises of physiotherapy (problem of communication and/or comprehension and/or physical inaptitude)
- Patient transplanted of a solid body, allograft or autograft of hematopoietic stem cells
- Patient with a seropositivity for the known HIV and cluster of differentiation 4 (CD4) \<250/mm3
Key Trial Info
Start Date :
June 6 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 11 2024
Estimated Enrollment :
82 Patients enrolled
Trial Details
Trial ID
NCT03861897
Start Date
June 6 2019
End Date
December 11 2024
Last Update
December 31 2024
Active Locations (11)
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1
Centre Hospitalier Universitaire Angers
Angers, France, 49000
2
Hôpital Victor Dupuy
Argenteuil, France, 95100
3
Hôpital de la Cavale Blanche
Brest, France, 29200
4
Centre Hospitalier de Cholet
Cholet, France, 49 300