Status:

COMPLETED

Frequency of Putative Enteric Zoster Diagnosed Using Saliva Samples in Patients With Abdominal Pain: a Prospective Study

Lead Sponsor:

Asan Medical Center

Conditions:

Abdominal Pain

Zoster With Other Complications

Eligibility:

All Genders

18-79 years

Phase:

NA

Brief Summary

The aim of this study is to identify the frequency of enteric zoster using salivary varicella zoster virus (VZV) DNA PCR in patients who visit the emergency room due to acute abdominal pain.

Detailed Description

Varicella zoster virus (VZV) infects and establishes latency in neurons in the ganglia of the cranial nerve, dorsal root, and enteric ganglia. VZV reactivation in enteric neurons (enteric zoster) can ...

Eligibility Criteria

Inclusion

  • Patients aged ≥ 18, and \< 80 years
  • ER-visited patients with acute abdominal pain
  • Numerical rating scale (NRS) score ≥ 4
  • Unresponsive to gastrointestinal motility drug, antacid

Exclusion

  • Unwilling or unable to give informed consent forms
  • Patients taking antiviral agents
  • Patients complaining mild abdominal pain (NRS score ≤ 3)

Key Trial Info

Start Date :

April 24 2019

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 31 2019

Estimated Enrollment :

50 Patients enrolled

Trial Details

Trial ID

NCT03862092

Start Date

April 24 2019

End Date

December 31 2019

Last Update

September 24 2020

Active Locations (1)

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Asan Medical Center, University of Ulsan College of Medicine

Seoul, South Korea, 138-736