Status:
COMPLETED
NAC Effect on Hox Genes Expressions in RIF
Lead Sponsor:
Royan Institute
Conditions:
Female Infertility
Eligibility:
FEMALE
22-40 years
Phase:
PHASE3
Brief Summary
Comparison of the group treated with NAC-supplementation and placebo- administered groups showed elevations in HOXA cluster genes (all members) expression level in endometrium of women with RIF.
Detailed Description
Despite significant developments in assistant reproductive technology (ART) that have overcome many underlying causes of infertility, pregnancy success rates remain relatively low, mainly due to impla...
Eligibility Criteria
Inclusion
- Age between 20 and 40 years old
- At least two IVF failure
- BMI in the normal range
Exclusion
- Irregular menstrual cycle
- Taking hormonal drugs except thyroid medication
- Abnormal karyotype or chromosomal disorders
- Coagulation problems.
Key Trial Info
Start Date :
February 1 2015
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 1 2017
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT03862586
Start Date
February 1 2015
End Date
July 1 2017
Last Update
March 5 2019
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