Status:
COMPLETED
E-Cigarette Effects on Markers of Cardiovascular and Pulmonary Disease
Lead Sponsor:
University of Wisconsin, Madison
Collaborating Sponsors:
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
Conditions:
Tobacco Use
E-Cigarette Use
Eligibility:
All Genders
18+ years
Brief Summary
This study is designed to enhance the understanding of the possible health effects of e-cigarette use by relating the acute and long-term use of e-cigarettes and conventional cigarettes ("products") t...
Detailed Description
E-cigarette use is increasing rapidly in the United States, especially amongst youth, underscoring the vital need to improve understanding of its health risks. Relevant data could inform policy, guide...
Eligibility Criteria
Inclusion
- able to read and write English
- no plans to quit smoking and/or e-cig use in the next month
- not using cigars/smokeless/snus tobacco \>/= 1 time per week
- having a stable pattern of current product use
- able to walk at least 2 blocks without assistance or stopping
- Specific to Exclusive Smokers:
- smokes daily
- \>/= 5 cigs/day for last 6 months
- \< 3 uses E-cigs in lifetime
- \>/= 5 ppm carbon monoxide (CO)
- Cotinine \> 100 ng/ml
- Specific to Exclusive E-cig users:
- \</= 2 days per month cigarette use for last 6 months
- \>/= 5 days per week E-cig use for last 3 months
- \</= 4 ppm CO
- Cotinine \> 100 ng/ml
- Specific to Never-users
- \< 100 cigarettes in a lifetime, none for \> 5 years
- \< 3 E-cig uses in a lifetime
- \</= 4 ppm CO
- Cotinine \< 100 ng/ml
Exclusion
- current use of a smoking cessation medication
- women who are pregnant or plan to get pregnant in the coming month
- women who might be pregnant
- incarcerated individuals
- history of sarcoidosis in past 5 years, or active interstitial lung/pulmonary fibrosis
- history of positive Coronavirus-19 test
Key Trial Info
Start Date :
March 5 2019
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
March 9 2022
Estimated Enrollment :
450 Patients enrolled
Trial Details
Trial ID
NCT03863509
Start Date
March 5 2019
End Date
March 9 2022
Last Update
August 21 2023
Active Locations (1)
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1
University of Wisconsin
Madison, Wisconsin, United States, 53792