Status:
COMPLETED
Hemodynamics During Induction of General Anesthesia After Prophylactic Ephedrine, Phenylephrine or Norepinephrine.
Lead Sponsor:
Helse Fonna
Conditions:
Hemodynamic Instability
Anesthesia, General
Eligibility:
FEMALE
18-50 years
Phase:
PHASE4
Brief Summary
In this trial the investigators want to examine if there is any difference in hemodynamic stability when giving equipotent prophylactic injections of ephedrine 0,1 mg/kg, phenylephrine 1 microg/kg, no...
Detailed Description
The LiDCOplus monitoring system (Lithium Dilutional Cardiac Output (LiDCO) Ltd., Cambridge, United Kingdom) is a minimally invasive monitor for measuring stroke volume (SV) using two different algorit...
Eligibility Criteria
Inclusion
- Healthy women
- Age 18-50 years
- Gynecological procedures
- General anesthesia
Exclusion
- Pre-existing hypertension
- Diabetes for several years
- Ischemic heart disease
- Cerebrovascular disease
- Heart valve disease
- Verified cardiac arrhythmia
- Anaemia
- Kidney or hepatic disease
- Hypersensitivity for soya, eggs or peanuts
- Pregnancy
- Poor health state
- Illicit substance use
- BMI \<20 or \>35 kg/m2
- SBP \>150 mmHg
- HR \>100 beats/min
Key Trial Info
Start Date :
March 15 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 14 2023
Estimated Enrollment :
128 Patients enrolled
Trial Details
Trial ID
NCT03864094
Start Date
March 15 2022
End Date
December 14 2023
Last Update
October 4 2024
Active Locations (1)
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1
Helse Fonna, Haugesund Sykehus
Haugesund, Norway