Status:
COMPLETED
The Comparison of Changes of QTc, Tp-e Interval, and Tp-e/QT Ratio, Tp-e/QTc Ratio on the ECG During Living Donor Liver Transplantation Under Desflurane and Total Intravenous Anesthesia -Randomized Controlled Trial
Lead Sponsor:
Yonsei University
Conditions:
Liver Cirrhosis(Who Will Undergo Planed Liver Transplantation)
Eligibility:
All Genders
20+ years
Phase:
NA
Brief Summary
Prolonged corrected QT interval (QTc) has been observed in about half of patients with liver cirrhosis. Marked prolongation of QTc (ie, 500 msec) has been considered to be a risk factor for fatal vent...
Eligibility Criteria
Inclusion
- patients with liver cirrhosis who will undergo planned liver transplantation
Exclusion
- 1\. emergent liver transplantation
- 2\. unstable angina
- 3\. recent MI(Myocardial Infarction)
- 4\. uncontrolled hypertension (diastolic BP \> 110mmHg)
- 5\. implantable cardiac defibrillator
- 6\. severe obesity (BMI\>30kg/m2)
- 7\. allergy to propofol
Key Trial Info
Start Date :
February 17 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 31 2020
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT03864276
Start Date
February 17 2019
End Date
December 31 2020
Last Update
October 15 2021
Active Locations (1)
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1
Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Yonsei University College of Medicine
Seoul, South Korea, 120-752