Status:
COMPLETED
MENIPREP Study: Evauation of the Effectiveness of Prp Injection in the Management of Degenerative Meniscal Lesions : Randomized Controlled Trial Double Blind Versus Reference Treatment"
Lead Sponsor:
Assistance Publique Hopitaux De Marseille
Conditions:
DEGENERATIVE MENISCAL LESIONS
Eligibility:
All Genders
20-80 years
Phase:
NA
Brief Summary
Meniscal tissue has very limited intrinsic properties in terms of repair, given the low mitotic activity of chondrocytes and poor vascularization. Nevertheless, its capacity for regeneration, in vivo ...
Eligibility Criteria
Inclusion
- Men and women aged 20 to 80
- MDD diagnosis objected to MRI (grade II/III)
- Joint pain for more than 3 month
- Absence of bone lesion or moderate knee osteoarthritis stage \<2 on the Kellgren Laurence scale (objectified on radiography in schuss) in the 6 months prior to inclusion
- Axial deformity of the lower limbs less than or equal to 5 °
- Signed consent signed by the patient
- Ability to perform procedures as part of the follow-up (walk 50 steps on a flat surface and up / down stairs).
- Be affiliated to a health insurance scheme
Exclusion
- Axial deformity\> 5 °
- Ligament instability
- Major injuries or surgery of the target knee or lateral contralateral knee in the 12 months preceding the inclusion visit
- Ligament reconstruction in the 12 months prior to the inclusion visit
- Need a cane or assistance to move
- BMI\> 35
- Thrombocytopenia \<150 G / L
- Thrombocytosis\> 450 G / L
Key Trial Info
Start Date :
April 1 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 4 2023
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT03866824
Start Date
April 1 2019
End Date
December 4 2023
Last Update
June 29 2025
Active Locations (1)
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1
Assistance Publique Hopitaux de Marseille
Marseille, France, 13354