Status:

UNKNOWN

Effects of tDCS on Depressive Symptoms of Participants With Temporal Lobe Epilepsy

Lead Sponsor:

Hospital de Clinicas de Porto Alegre

Conditions:

Depressive Symptoms

Epilepsy, Temporal Lobe

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

This project was developed to analyze the clinical, biochemical and functional impact of tDCS on depressive symptoms in participants with temporal lobe epilepsy, intending to collaborate directly in t...

Detailed Description

Transcranial direct current stimulation (tDCS) has emerged as an alternative tool in the treatment of participants with mood disorders and may also benefit the treatment of participants with epilepsy....

Eligibility Criteria

Inclusion

  • Patients older than 18 years.
  • Diagnosis of Temporal Lobe Epilepsy based on clinical, electrophysiological, magnetic resonance (MRI) and computed tomography (CT) imaging of the brain.
  • Patients will be selected who are able to adequately complete the self-administered questionnaires and handle the home tDCS equipment.
  • 13 points or more on the Beck Depression Inventory.

Exclusion

  • Clinical history suggestive of other paroxysmal abnormalities other than temporal lobe epilepsy, such as syncope, psychogenic seizures, or transient vascular accident;
  • Change in the antiepileptic regime in the last 30 days;
  • History of status epilepticus on last year;
  • Performed vagus nerve stimulation (VNS), Deep Brain Stimulation (DBS) or other neurostimulation \<1 year prior to study;
  • Active suicide plane;
  • Contraindication for tDCS, including head injury, metal on the head or any implanted medical device, including pacemakers and cardiac defibrillators;
  • Pregnancy.

Key Trial Info

Start Date :

July 1 2018

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

July 1 2019

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT03871842

Start Date

July 1 2018

End Date

July 1 2019

Last Update

March 12 2019

Active Locations (1)

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1

Hospital de Clínicas de Porto Alegre

Porto Alegre, Rio Grande do Sul, Brazil, 90040-000