Status:

UNKNOWN

Biodiversity Intervention and Atopic Sensitization

Lead Sponsor:

University of Helsinki

Collaborating Sponsors:

Tampere University

Pirkanmaa Hospital District (Pirkanmaan sairaanhoitopiiri)

Conditions:

Atopy

Allergy

Eligibility:

All Genders

Up to 1 years

Phase:

NA

Brief Summary

Children will receive biodiversity intervention or placebo. The proof of concept trial is double blind. Intervention will start at the age of 2 months and last 10 months. Children will be randomized t...

Detailed Description

Newborns will start to be exposed to biodiversity intervention or placebo at the age of two months. The proof of concept trial will be double blind. Intervention will start at the age of 2 months and ...

Eligibility Criteria

Inclusion

  • both parents have atopy
  • newborn

Exclusion

  • severe disease, particularly immune system deficiency or down syndrome or cancer
  • medication affecting immune system
  • birth before week 35 in pregnancy
  • being a twin
  • only one of the parents have atopy
  • none of the parents have atopy
  • children have passed the age of two months
  • immune system disorder such as rheumatoid disease, colitis ulcerosa, Crohn disease, diabetes or genetic risk to type 1 diabetes
  • no participation in national vaccination programme

Key Trial Info

Start Date :

March 25 2019

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 31 2025

Estimated Enrollment :

350 Patients enrolled

Trial Details

Trial ID

NCT03872219

Start Date

March 25 2019

End Date

December 31 2025

Last Update

March 13 2019

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Biodiversity Intervention and Atopic Sensitization | DecenTrialz