Status:
ACTIVE_NOT_RECRUITING
Resiliency Training in Adolescents With NF1 and NF2
Lead Sponsor:
Massachusetts General Hospital
Collaborating Sponsors:
United States Department of Defense
Conditions:
Neurofibromatoses
Eligibility:
All Genders
12-17 years
Phase:
NA
Brief Summary
This randomized controlled trial for resiliency training in adolescents with Neurofibromatosis 1 and Neurofibromatosis 2 via secure live video to determine the efficacy two stress and symptom manageme...
Detailed Description
Neurofibromatosis (NFs) are rare genetic conditions with cure. Adolescents with NF experience more symptoms of depression and anxiety, higher levels of stress associated with coping with NF symptoms, ...
Eligibility Criteria
Inclusion
- Has a diagnosis of NF1 or NF2 and is between the ages of 12-17
- Is capable of completing and fully understanding the informed consent process/assent and the study procedures and assessments in English; has parental approval for participation
- English speaking and at least a 3rd grade self-reported and parent reported reading level
- Self reported/parent reported difficulties coping with stress and NF symptoms
Exclusion
- Has major medical co-morbidity not NF related expected to worsen in the next 12 months
- Recent (within past 3 months) change in antidepressant medication
- Recent participation in cognitive behavioral therapy or relaxation therapy (within past 3 months)
- Has significant mental health diagnosis requiring immediate treatment (e.g., untreated bipolar disorder, psychotic disorder, active substance dependence)
- Unable or unwilling to complete assessments electronically via REDCap
- Unable or unwilling to participate in group videoconferencing sessions
- Unable or unwilling to participate along with at least 1 parent in a video screening session
Key Trial Info
Start Date :
December 15 2019
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
February 20 2026
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT03873610
Start Date
December 15 2019
End Date
February 20 2026
Last Update
December 26 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Massachusetts General Hospital
Boston, Massachusetts, United States, 02140