Status:
TERMINATED
Biochemical Makers for Outcome After Pediatric out-of Hospital Cardiac Arrest
Lead Sponsor:
Brno University Hospital
Conditions:
Out-Of-Hospital Cardiac Arrest
Eligibility:
All Genders
14-19 years
Brief Summary
This single-center study will validate serum, imaging and clinical markers to determine outcome of pediatric patients early after Out-of-Hospital cardiac arrest (OHCA). Results are expected to add to ...
Detailed Description
Cardiac arrest (CA) is an important cause of mortality and morbidity in pediatric patients. Yearly incidence of CA is 7- 8 cases per 100000 children. Hypoxia is the leading cause of OHCA with up to 1/...
Eligibility Criteria
Inclusion
- Children between 2 weeks -18 years of age
- Child who suffered an out of hospital CA: defined as "Cessation of cardiac mechanical activity as confirmed by the absence of signs of circulation. Includes the following rhythms: pulseless electrical activity (PEA), asystole, ventricular tachycardia, and ventricular fibrillation" with the need od chest compressions.
- Children admitted to the Department of pediatric anesthesia and intensive care
- Children have vascular access for blood draws as part of their standard of care
- Children have a pre-CA Pediatric Cerebral Performance Category (PCPC) score of 1- 3.
Exclusion
- Patients with brain injury of other etiologies. (trauma, abscess, tumor, bacterial meningitis)
- Children with do not resuscitate (DNR) status
- Pregnancy
- Metabolic or other disease affecting the brain (eg. refractory epilepsy)
Key Trial Info
Start Date :
May 17 2019
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
October 31 2020
Estimated Enrollment :
4 Patients enrolled
Trial Details
Trial ID
NCT03873662
Start Date
May 17 2019
End Date
October 31 2020
Last Update
November 30 2020
Active Locations (1)
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1
University hospital Brno
Brno, State, Czechia, 62500