Status:

COMPLETED

CLEAR SYNERGY Neutrophil Substudy

Lead Sponsor:

NYU Langone Health

Collaborating Sponsors:

Population Health Research Institute

National Heart, Lung, and Blood Institute (NHLBI)

Conditions:

Neutrophils.Hypersegmented | Bld-Ser-Plas

STEMI - ST Elevation Myocardial Infarction

Eligibility:

All Genders

19-110 years

Brief Summary

CLEAR SYNERGY is an international multi center 2x2 randomized placebo controlled trial of colchicine and spironolactone in patients with STEMI. Subjects enrolled in the main CLEAR SYNERGY trial will b...

Eligibility Criteria

Inclusion

  • Patients who are randomized to the drug RCT portion of the CLEAR SYNERGY (OASIS 9) trial will be eligible for participation in this Neutrophil biomarker substudy.

Exclusion

  • Use of anti-inflammatory agents (except aspirin)
  • Active infection

Key Trial Info

Start Date :

March 4 2019

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

August 9 2024

Estimated Enrollment :

322 Patients enrolled

Trial Details

Trial ID

NCT03874338

Start Date

March 4 2019

End Date

August 9 2024

Last Update

September 19 2024

Active Locations (1)

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1

NYU School of Medicine

New York, New York, United States, 10016