Status:
WITHDRAWN
Neural Mechanisms of Mindfulness-based Cognitive Therapy (MBCT) for Posttraumatic Stress Disorder (PTSD)_VA Only
Lead Sponsor:
Ohio State University
Collaborating Sponsors:
National Institute of Mental Health (NIMH)
Conditions:
Post Traumatic Stress Disorder
Eligibility:
All Genders
18-72 years
Phase:
NA
Brief Summary
This study will examine the effects of psychotherapy as treatment for PTSD. This research will see how brain activity and brain connectivity is affected by Mindfulness Based Cognitive Therapy (MBCT) a...
Detailed Description
Note: due to COVID precautions, treatment shifted from in-person to remote ("Zoom" videoconferencing)
Eligibility Criteria
Inclusion
- Meets current Diagnostic and Statistical Manual of Mental Disorders, fifth edition (DSM-5) criteria for PTSD (with or without Major Depressive Disorder) or subsyndromal PTSD (qualifying trauma, and at least one intrusive, one avoidant, one negativity, and one arousal symptoms, and significant impairment or distress); type of trauma shall include interpersonal violence - combat, physical assault, sexual assault, etc.
Exclusion
- Dissociative PTSD
- Delayed-onset PTSD
- Magnetic Resonance Imaging (MRI) contraindications (e.g. metal in body, inability to be in the scanner - claustrophobia, severe back pain, etc.)
- Serious medical or neurologic conditions (e.g. stroke, seizures)
- Suicide risk
- Psychosis
- Life history of schizophrenia
- Life history of bipolar disorder
- Current severe substance use disorder
- Other factors that preclude safe and meaningful participation in the study, at discretion of the PI and study team
Key Trial Info
Start Date :
January 29 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2023
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT03874845
Start Date
January 29 2022
End Date
June 1 2023
Last Update
October 23 2023
Active Locations (2)
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1
VA Ann Arbor Healthcare System
Ann Arbor, Michigan, United States, 48105
2
The Ohio State University
Columbus, Ohio, United States, 43210