Status:

COMPLETED

Next-Generation Pre-Operative Targeting for Thalamic DBS in the Treatment of Tremor

Lead Sponsor:

Mayo Clinic

Conditions:

Essential Tremor

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Researchers are investigating improved methods of targeting deep brain stimulators for treatment of essential tremor relying on brain connectivity measures derived from MRI.

Eligibility Criteria

Inclusion

  • Diagnosis of refractory essential tremor scheduled for unilateral thalamic deep brain stimulator placement
  • Age ≥ 18 years

Exclusion

  • Prior deep brain stimulator, stereotactic radiosurgery, or focused ultrasound procedure for treatment of tremor
  • Presence of concomitant movement disorder (e.g. Parkinson's disease, dystonia, etc.)
  • Known pre-existing structural brain abnormality (e.g, infarction, tumor, prior brain surgery, etc.)
  • Contraindication to 3 Tesla brain MRI (e.g. incompatible implanted device)
  • Pregnant

Key Trial Info

Start Date :

March 20 2019

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

February 12 2021

Estimated Enrollment :

9 Patients enrolled

Trial Details

Trial ID

NCT03875404

Start Date

March 20 2019

End Date

February 12 2021

Last Update

September 17 2021

Active Locations (1)

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Mayo Clinic in Florida

Jacksonville, Florida, United States, 32224