Status:

RECRUITING

Change of Adipose Tissues and Triglyceride After Bariatric Surgery or Life-style Intervention

Lead Sponsor:

Chinese University of Hong Kong

Conditions:

Non-Alcoholic Fatty Liver Disease

Obesity, Morbid

Eligibility:

All Genders

18-65 years

Phase:

NA

Brief Summary

The study is aimed * To quantify the change of adipose tissues, triglyceride in liver and pancreas and cholesterol after lifestyle intervention or bariatric surgery. * To test the hypothesis that Bro...

Detailed Description

Obesity is associated with different chronic disorders such as metabolic syndrome, non-alcoholic fatty liver disease (NAFLD) and diabetes mellitus type 2 (DM2). It can be classified into mild, moderat...

Eligibility Criteria

Inclusion

  • BMI ≥ 25-30 kg/m2
  • BMI ≥ 30 kg/m2 with Metabolic syndrome
  • BMI ≥ 35 kg/m2 for morbid obesity

Exclusion

  • Other kind of hepatic diseases
  • Under medications known to affect liver fat
  • Waist circumference ≥ 150 cm
  • Weight ≥ 250 kg
  • MRI contraindications

Key Trial Info

Start Date :

April 1 2019

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

June 30 2026

Estimated Enrollment :

80 Patients enrolled

Trial Details

Trial ID

NCT03875625

Start Date

April 1 2019

End Date

June 30 2026

Last Update

February 13 2025

Active Locations (1)

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1

The Chinese University of Hong Kong, Prince of Wale Hospital

Hong Kong, Shatin, Hong Kong