Status:
COMPLETED
The Trauma INtramuscular Tranexamic Acid Clinical Trial
Lead Sponsor:
London School of Hygiene and Tropical Medicine
Collaborating Sponsors:
Barts & The London NHS Trust
St George's University Hospitals NHS Foundation Trust
Conditions:
Traumatic Haemorrhage
Eligibility:
All Genders
16+ years
Phase:
PHASE1
PHASE2
Brief Summary
Intramuscular injection of tranexamic acid (TXA) would increase its use in situations where administration of intravenous drugs is difficult. The investigators aim to assess the population pharmacokin...
Detailed Description
A prospective, open-label, multicentre, pharmacokinetic study conducted in the UK hospital. Potential eligible patients will have received a 1 gram IV dose of TXA at the scene of the injury or on arri...
Eligibility Criteria
Inclusion
- Adult (appear to be at least 16 years old) trauma patients who have received 1 gram of intravenous TXA for the management of haemorrhage in whom a second dose is clinically indicated are eligible.
Exclusion
- none
Key Trial Info
Start Date :
September 17 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 12 2020
Estimated Enrollment :
31 Patients enrolled
Trial Details
Trial ID
NCT03875937
Start Date
September 17 2019
End Date
February 12 2020
Last Update
April 10 2020
Active Locations (2)
Enter a location and click search to find clinical trials sorted by distance.
1
The Royal London Hospital
London, United Kingdom, E1 1FR
2
St George's Hospital
London, United Kingdom, SW17 0QT