Status:

RECRUITING

Vaginal Native Tissues Repair for Pelvic Organ Prolapse

Lead Sponsor:

University Hospital, Limoges

Conditions:

Prolapse, Vaginal

Eligibility:

FEMALE

50+ years

Phase:

NA

Brief Summary

The aim of the study is to assess at one year the effectiveness of the vaginal patch plastron in comparison of the anterior colporraphy through a combined definition of success: anatomic and functiona...

Detailed Description

Pelvic organ prolapse is usually the result of loss of pelvic support. It is widely accepted that 50% of women after 50 years old will develop prolapse, evaluated through the POPQ Classification . Pel...

Eligibility Criteria

Inclusion

  • Patient at 50 years of age or older
  • Symptomatic primary prolapse of the anterior vaginal wall defined by Aa and/or Ba points ≥0 according to the POP-Q system
  • A positive response to the question "Do you usually have a bulge or something falling out that you can see or feel in your vaginal area?" (question 3 of the PFDI-20)
  • Able to give informed consent
  • Performans Status score ≤ 2

Exclusion

  • Patient with need for surgical treatment for myorraphy of levator ani muscles
  • Patient with previous surgical cystocele repair.
  • Patient with evolving gynaecologic cancer.
  • Pregnancy or wish for future pregnancy, lactating woman.
  • Inability to participate in study follow-up or to provide informed consent.
  • Lack of social insurance .

Key Trial Info

Start Date :

September 27 2019

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

March 27 2028

Estimated Enrollment :

214 Patients enrolled

Trial Details

Trial ID

NCT03875989

Start Date

September 27 2019

End Date

March 27 2028

Last Update

August 29 2023

Active Locations (9)

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Page 1 of 3 (9 locations)

1

CHU de Bordeaux

Bordeaux, France, 33000

2

CH de Brive

Brive-la-Gaillarde, France, 19100

3

CHU de Clermont Ferrand

Clermont-Ferrand, France, 63100

4

CH de Gueret

Guéret, France, 23000