Status:
UNKNOWN
Analysis of the Variation in Caspase-8 Availability and Cleavage in Oral Squamous Cell Carcinoma
Lead Sponsor:
Guy's and St Thomas' NHS Foundation Trust
Conditions:
Oral Cancer
Eligibility:
All Genders
18+ years
Brief Summary
Control of cell death is frequently disrupted in cancer resulting in overgrowth of tumour cells. Caspase-8 is a key enzyme involved in controlling cell death. This study examines the importance of cas...
Detailed Description
Control of cell death is frequently disrupted in cancer resulting in overgrowth of tumour cells. The caspase family of enzymes are the key performers of controlled cell death and caspase-8 is frequent...
Eligibility Criteria
Inclusion
- Oral cancer
- Sufficient follow up data
Exclusion
- Patient has indicated that they do not wish their tissue to be used for research.
- . The quantity or quality of tissue is too little or poor to provide adequate material without significant reserve.
- The material contains bone.
Key Trial Info
Start Date :
November 11 2017
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
January 30 2021
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT03877159
Start Date
November 11 2017
End Date
January 30 2021
Last Update
July 22 2020
Active Locations (1)
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1
Robert Kennedy
London, United Kingdom, SE19RT