Status:

UNKNOWN

Effect of Empagliflozin on Body Composition and Ketones

Lead Sponsor:

Seoul National University Bundang Hospital

Conditions:

Diabetes Mellitus

Fat; Intolerance, Pancreas

Eligibility:

All Genders

20+ years

Phase:

PHASE4

Brief Summary

The purpose of this study is to evaluate changes of body composition induced by Sodium-glucose cotransporter-2 (SGLT2) inhibitor and its metabolic consequence in Korean type 2 diabetes (T2D).

Detailed Description

Sodium-glucose cotransporter-2 (SGLT2) inhibitor increases urinary excretion of glucose, promoting glycemic control and weight loss. However, it is unclear whether weight loss is attributed to decreas...

Eligibility Criteria

Inclusion

  • Patients with type 2 diabetes Age: 20-79 years BMI ≥ 20 kg/m2 eGFR ≥ 45

Exclusion

  • Patients with type 1 diabetes Secondary diabetes due to Cushing diseases, acromegaly Insulin user BMI \< 20 kg/m2 eGFR \< 45 Malignancy

Key Trial Info

Start Date :

August 1 2018

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 31 2023

Estimated Enrollment :

200 Patients enrolled

Trial Details

Trial ID

NCT03877406

Start Date

August 1 2018

End Date

December 31 2023

Last Update

August 14 2023

Active Locations (1)

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1

Seoul National University Bundang Hospital

Seongnam-si, Gyeonggi-do, South Korea, 463-707