Status:

COMPLETED

Effect of Nusinersen on Adults With Spinal Muscular Atrophy

Lead Sponsor:

Northwell Health

Conditions:

Adult Spinal Muscular Atrophy

Eligibility:

All Genders

18-60 years

Brief Summary

Observational study of adult patients with spinal muscular atrophy types 2 and 3 receiving nusinersen

Detailed Description

Observational study to assess effects of nusinersen on motor function in adult patients with spinal muscular atrophy who are both ambulatory and non-ambulatory. Subjects will receive standard of care ...

Eligibility Criteria

Inclusion

  • Genetically confirmed 5q SMA
  • ability to access intrathecal space for nusinersen injection

Exclusion

  • Renal impairment
  • thrombocytopenia
  • inability to access intrathecal space by CT or flouro guided injection

Key Trial Info

Start Date :

April 1 2019

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

July 13 2021

Estimated Enrollment :

12 Patients enrolled

Trial Details

Trial ID

NCT03878030

Start Date

April 1 2019

End Date

July 13 2021

Last Update

March 20 2023

Active Locations (1)

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Northwell Health Neuroscience

Great Neck, New York, United States, 11021