Status:

UNKNOWN

Influence of Morphine or Ketamine or Saline Applied During In-hospital Cardiopulmonary Resuscitation on Early Survival

Lead Sponsor:

University Hospital, Akershus

Conditions:

Cardiac Arrest

Eligibility:

All Genders

18+ years

Phase:

PHASE1

Brief Summary

A small numbers of patients (10-15%) treated with cardiopulmonary resuscitation (CPR) are discharged from hospitals with a favorable neurologic outcome. However, a higher incidence of chest injuries (...

Detailed Description

Almost 35 years ago, Dr Peter Safar wrote that "cerebral recovery from more than 5 min of cardiac arrest is hampered by complex secondary derangements of multiple organ systems after reperfusion". Act...

Eligibility Criteria

Inclusion

  • \- All adult patients with in-hospital cardiac arrest

Exclusion

  • an age of less than 18 years
  • drugs poisoning or the administration of opioids or Ketamine 24 hours before the cardiac arrest
  • terminal phase of oncological or other chronic diseases
  • poor communication and physical capabilities due to psychiatric or neurological diseases
  • dementia or Alzheimers
  • extremely reduced weight or physical ability and activity
  • known history of chronic use of opioids/Ketamine

Key Trial Info

Start Date :

October 1 2021

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

January 1 2026

Estimated Enrollment :

240 Patients enrolled

Trial Details

Trial ID

NCT04009759

Start Date

October 1 2021

End Date

January 1 2026

Last Update

June 11 2021

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