Status:
COMPLETED
Non-invasive Diagnosis of Pulmonary Embolism by Use of Biomarkers in Exhaled Breath Condensate
Lead Sponsor:
Aalborg University Hospital
Collaborating Sponsors:
University of Aarhus
Conditions:
Pulmonary Embolism
Eligibility:
All Genders
18+ years
Brief Summary
In this study, a new, non-invasive method for diagnosis of pulmonary embolism (PE) will be tested. In pre-clinical studies, we have identified 151 putative biomarkers for pulmonary embolism in the exh...
Detailed Description
The study will compare the protein profiles of EBC collected from patients admitted to the department of cardiology with suspected pulmonary embolism and controls with same age (within a range of 10 y...
Eligibility Criteria
Inclusion
- Inclusion Criteria - Suspected/confirmed PE patients:
- Admitted to the emergency department with initial diagnosis of PE, visited to the Department of Cardiology at Aalborg University Hospital.
- Are conscious and able to understand the given study information.
- Possess legal capacity.
- Age above 18 years.
- Informed, signed consent is obtained.
- Clinically stable, which is defined as patients with stable blood pressure and not in need for other treatments .
- No need for organ support, which comprises need for vasopressors or inotropes, mechanical ventilation, extra corporal circulation or renal replacement therapy.
- Inclusion Criteria - Controls:
- • Patients as the PE patients, but where the diagnosis of PE is rejected.
- The rest of the control persons will be recruited as described:
- Patients who are going to have elective procedures at the Department of Cardiology, Aalborg University Hospital.
- Same gender and age (within a 10-year range) as an included PE patient.
- Are conscious and able to understand the given study information.
- Possess legal capacity.
- Age above 18 years.
- Informed, signed consent is obtained.
- Exclusion Criteria:
- Active malignant disease (i.e. ongoing anti-cancer therapy or palliation).
- Current smokers
Exclusion
Key Trial Info
Start Date :
April 8 2019
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
May 31 2020
Estimated Enrollment :
110 Patients enrolled
Trial Details
Trial ID
NCT04010760
Start Date
April 8 2019
End Date
May 31 2020
Last Update
February 15 2022
Active Locations (1)
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1
Aalborg Hospital
Aalborg, Denmark, 9000