Status:
COMPLETED
Wool Clothing for the Management of Childhood Atopic Dermatitis (DESSINE2)
Lead Sponsor:
Murdoch Childrens Research Institute
Collaborating Sponsors:
Australian Wool Innovation Ltd
Northwestern University
Conditions:
Dermatitis, Atopic
Eligibility:
All Genders
3-5 years
Phase:
NA
Brief Summary
The study is a sequentially recruited, cross-over-cohort, outpatient-based evaluation of the effectiveness of wool clothing, as compared to standard clothing, in reducing the severity of childhood ato...
Detailed Description
The study will aim for a sample size of approximately 150 participants (equally distributed between 3 international sites) between the ages of 3 months and 5 years referred to the respective Dermatolo...
Eligibility Criteria
Inclusion
- Is aged between 3 months and 5 years of age at the time of recruitment
- Has moderate to severe eczema as determined by an EASI score of 7 or above at their initial visit
- Has a legally acceptable representative capable of understanding the informed consent document and providing consent on the participants behalf
Exclusion
- Has a known allergic contact dermatitis to wool or merino wool
- Is unable to attend all scheduled visits
- Has unstable eczema defined by an escalation of treatment requirements during the preceding 6 weeks. This would include flares of AD for any reason including infection, food allergy etc.
- Use of systemic corticosteroids within 6 weeks of study start.
- Any medical reason that is considered by the principal investigator to preclude enrolment.
Key Trial Info
Start Date :
September 23 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 31 2024
Estimated Enrollment :
19 Patients enrolled
Trial Details
Trial ID
NCT04011215
Start Date
September 23 2019
End Date
October 31 2024
Last Update
May 25 2025
Active Locations (1)
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1
Northwestern University, Skin Disease Research Center, Lurie Children's Hospital
Chicago, Illinois, United States, 60611