Status:
SUSPENDED
Measurement Of NT-proBNP to Predict Outcomes in Surgery
Lead Sponsor:
Julie Dawson
Conditions:
Vascular Surgical Procedure
Eligibility:
All Genders
18+ years
Brief Summary
The team is investigating whether N-terminal pro B-type natriuretic peptide (NT-proBNP) and other cardiac markers are useful for predicting outcomes for patients undergoing vascular surgery. By measur...
Detailed Description
Almost 1 in 5 patients who have elective major vascular surgery experience death or a myocardial infarction (MI) at 18 months post-surgery. Research has shown that peri-operative interventions may imp...
Eligibility Criteria
Inclusion
- Patients who are equal to or over 18 years old
- Patients scheduled to undergo elective surgery for the following procedures:
- Infrainguinal arterial reconstruction
- Aortic aneurysm
- Aorto-bifemoral bypass / or aortic endarterectomy
- Femoro-popliteal bypass
- Femoro-distal bypass
- Femoral endarterectomy
- Femoro-femoral crossover
- Axillo-femoral bypass
- Elective carotid surgery
- Patients having either general or regional anaesthesia for their surgery
Exclusion
- Patients undergoing emergency surgery
- Those who are unable or unwilling to give informed consent
- Patients with unstable coronary syndromes (acute or recent MI with evidence of important ischemic risk by clinical symptoms or stress testing or unstable or severe angina pectoris)
- Patients with decompensated heart failure (new onset shortness of breath and rales together with echocardiographic evidence of cardiac dysfunction or deterioration of chronic heart failure despite heart failure therapy)
- Patients with chronic atrial fibrillation
Key Trial Info
Start Date :
September 5 2019
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
September 1 2025
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT04014647
Start Date
September 5 2019
End Date
September 1 2025
Last Update
December 22 2023
Active Locations (1)
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1
Norfolk & Norwich University Hospitals NHS Foundation Trust
Norwich, Norfolk, United Kingdom, NR4 7UY