Status:

RECRUITING

Evaluation of Central Sensitization, Fear-Avoidance, and Pain-Pressure Threshold With Chronic Pain After Hysterectomy

Lead Sponsor:

KK Women's and Children's Hospital

Conditions:

Hysterectomy

Chronic Pain

Eligibility:

FEMALE

21-80 years

Brief Summary

Phase 1 (started in July 2019): Central Sensitization Inventory (CSI), Fear-Avoidance Components Scale (FACS), pain-pressure threshold are factors associated with chronic post-hysterectomy pain (CPHP...

Detailed Description

Phase 1 (started in July 2019): Chronic post-surgical pain is persistent pain after a surgical procedure that lasts for at least 3 months with other causes of pain excluded. It is a major socioeconom...

Eligibility Criteria

Inclusion

  • Age 21 to 80 years old
  • American Society of Anesthesiologists Physical Scale (ASA) I to III
  • Benign gynaecological indications for hysterectomy
  • Elective abdominal or laparoscopic hysterectomy

Exclusion

  • Vaginal hysterectomy
  • Uterine prolapse, endometriosis, malignant disease, or pelvic pain as main indication for surgery
  • History of drug dependence or recreational drug use
  • History of chronic pain syndrome
  • Current chronic daily treatment with corticosteroids, excluding inhaled steroids
  • Allergy to study drugs
  • Major heart surgery
  • Heart transplant
  • Pacemaker inserted
  • Baseline non-sinus cardiac rhythm

Key Trial Info

Start Date :

July 23 2019

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 1 2027

Estimated Enrollment :

436 Patients enrolled

Trial Details

Trial ID

NCT04014829

Start Date

July 23 2019

End Date

December 1 2027

Last Update

November 26 2024

Active Locations (1)

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KK Women's and Children's Hospital

Singapore, Singapore, 229899