Status:
TERMINATED
Effectiveness of IPT-G in Major Depression
Lead Sponsor:
Hospital de Clinicas de Porto Alegre
Conditions:
Depressive Disorder, Major
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
Although antidepressants are the primary treatment for major depression, response and remission rates are unsatisfactory. The primary objective of this study is to identify if adding interpersonal gro...
Detailed Description
Patients presenting a current unipolar depression episode (BDI-II \> 18) without response to 2 adequate antidepressants trials (optimized by dose and time) will be randomly allocated to two arms: a) T...
Eligibility Criteria
Inclusion
- Diagnosis of Major Depressive Episode evaluated by the MINI-plus instrument.
- Patients attending the depression outpatient clinic (HCPorto Alegre) for 6 months or more
- History of two previous appropriate antidepressant treatments (dose: equivalent of 75 mg / day of amitriptyline and time: the minimum of four weeks)
- Beck Depression Inventory scores above 18.
Exclusion
- Patients with bipolar disorder
- Patients with substance abuse disorder,
- Patients with risk of suicide
- Patients with antisocial personality disorder
- Patients with psychotic syndrome,
- Patients with intellectual disability
- Patients receiving some kind of psychotherapy at the present time and in the last four weeks.
- Patients who are unable to communicate.
- Patients with Dismissive Attachment Style
Key Trial Info
Start Date :
August 25 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 20 2021
Estimated Enrollment :
18 Patients enrolled
Trial Details
Trial ID
NCT04015206
Start Date
August 25 2019
End Date
March 20 2021
Last Update
March 25 2021
Active Locations (1)
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1
Hospital de Clinicas de Porto Alegre
Porto Alegre, Rio Grande do Sul, Brazil, 90035-903