Status:

ACTIVE_NOT_RECRUITING

Imaging to Improve Brain Stimulation

Lead Sponsor:

VA Office of Research and Development

Collaborating Sponsors:

VA Palo Alto Health Care System

Brown University

Conditions:

Depressive Disorder

Eligibility:

All Genders

18-80 years

Brief Summary

This study investigates how brains change as a result of a treatment for depression called repetitive transcranial magnetic stimulation (rTMS). People who receive rTMS will have pictures of their brai...

Detailed Description

Veteran patients can be referred to receive a Neuromodulation Clinic consult at the Providence VA Medical Center (PVAMC). Following this consultation, patients who are to begin rTMS therapy for the tr...

Eligibility Criteria

Inclusion

  • Veteran beginning TMS therapy for the treatment of MDD at the Providence VAMC Neuromodulation Clinic
  • Age between 18 and 80 years
  • Able to read, verbalize, understand, and voluntarily sign the informed consent form
  • Structured Clinical Interview for DSM-5 (SCID-5) confirmed diagnosis of MDD

Exclusion

  • Contraindications to MRI (e.g. implanted metal or electronic devices)
  • Montreal Cognitive Assessment (MoCA) score \< 26
  • Pregnant

Key Trial Info

Start Date :

October 24 2019

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

December 31 2025

Estimated Enrollment :

42 Patients enrolled

Trial Details

Trial ID

NCT04016402

Start Date

October 24 2019

End Date

December 31 2025

Last Update

May 4 2025

Active Locations (2)

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Page 1 of 1 (2 locations)

1

VA Palo Alto Health Care System, Palo Alto, CA

Palo Alto, California, United States, 94304-1207

2

Providence VA Medical Center, Providence, RI

Providence, Rhode Island, United States, 02908-4734