Status:

UNKNOWN

Asynchronies in Pediatric Noninvasive Ventilation

Lead Sponsor:

Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico

Conditions:

Pediatric Respiratory Diseases

Eligibility:

All Genders

1-4 years

Phase:

NA

Brief Summary

The term ''Non-invasive ventilation'' (NIV) refers to various methods of respiratory assistance, in the absence of an indwelling endotracheal tube. In recent years, the use of NIV has increased for th...

Detailed Description

After having obtained the signed informed consent from the parents of the patient, a 6 Fr pediatric esophageal balloon-catheter will be placed through a nostril in the distal third of the esophagus. ...

Eligibility Criteria

Inclusion

  • Patients with acute hypoxic (SpO2/FIO2 ratio \< 315) or hypercapnic (PvCO2 \> 52 mmHg and venous pH \<7.28) respiratory failure in which non-invasive respiratory support is clinically indicated
  • Age: \> 28 days and \< 4 years
  • Patients whose parents provided signed informed consent

Exclusion

  • Age \> 4 years or \< 28 days
  • Patients whose parents did not provide signed informed consent
  • Clinical contraindications to non-invasive ventilation
  • Clinical contraindication to the placement of an esophageal balloon

Key Trial Info

Start Date :

September 15 2019

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

July 15 2021

Estimated Enrollment :

12 Patients enrolled

Trial Details

Trial ID

NCT04017780

Start Date

September 15 2019

End Date

July 15 2021

Last Update

November 27 2019

Active Locations (1)

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Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico

Milan, Italy, 20122